Mme Magali Blaud

Maître de conférences Université Paris CitéCiTCoM
Tel :: Numéro

Informations

Recherche :

  • Production et purification de protéines recombinantes en système procaryotes
  • Extraction, purification et analyse des acides nucléiques
  • Caractérisation des interactions entre biomolécules (protéines / acides nucléiques)
  • Etudes fonctionnelles d’activités enzymatiques
  • Caractérisation biophysique : spectrométrie, fluorescence et dichroïsme circulaire
  • Etude structurale : cristallographie, cryo-ME et SAXS

Activités :

  • Directrice-adjointe du département d’enseignement « Chimie et physico-chimie du médicament »
  • Responsable de l’unité pédagogique de « Biologie structurale »
  • Responsable de la spécialisation « Biologie Recherche » du POP I&R de la Faculté de Pharmacie
  • Responsable pour l’encadrement des stages pour le cursus Pharmasciences
  • Membre élu au conseil de gestion de la Faculté de Pharmacie
  • Ambassadrice en pédagogie à la FEBS « Fédération of European Biochemical Soieties »
  • Membre élu au conseil d’administration et responsable du GTE « Groupe de Travail sur l’Enseignement » de la SFBBM « Société Française de Biochimie et Biologie Moléculaire »
  • Responsable du BAG de SAXS pour le synchrotron SOLEIL (proposal 2017 puis 2019)

Publications :

  1. Ajjaji, D et al.(2022)Hepatitis C virus core protein uses triacylglycerols to fold onto the endoplasmic reticulum membrane. Traffic 23 (1):63-80.
  2. Vayssières, M, Bourgeois, G, Chardon, F, Tillault, AS, Blaud, M(2021)Detection and Labeling of Small Non-Coding RNAs by Splinted Ligation. Methods Mol Biol 2300 :65-72.
  3. Blaud, A, Maïder, A, Clark, IM(2021)Quantification of Ammonia Oxidizing Bacterial Abundances in Environmental Samples by Quantitative-PCR. Methods Mol Biol 2232 :135-146.
  4. Duval, R et al.(2020)A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in Plasmodium falciparum. Molecules 25 (21):.
  5. Clark, IM et al.(2020)Edaphic factors and plants influence denitrification in soils from a long-term arable experiment. Sci Rep 10 (1):16053.
  6. Sissoko, A et al.(2020)A Chemically Stable Fluorescent Mimic of Dihydroartemisinin, Artemether, and Arteether with Conserved Bioactivity and Specificity Shows High Pharmacological Relevance to the Antimalarial Drugs. ACS Infect Dis 6 (7):1532-1547.
  7. Fu, Q et al.(2020)Effects of urease and nitrification inhibitors on soil N, nitrifier abundance and activity in a sandy loam soil. Biol Fertil Soils 56 (2):185-194.
  8. Colucci-Guyon, E et al.(2019)Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probe. Chem Sci 10 (12):3654-3670.
  9. Malik, AA et al.(2018)Land use driven change in soil pH affects microbial carbon cycling processes. Nat Commun 9 (1):3591.
  10. Robert-Paganin, J et al.(2017)Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding. Nucleic Acids Res 45 (3):1539-1552.
  11. Bandje, K et al.(2016)Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum. Malar J 15 :248.
  12. Choudhary, S, Blaud, A, Osborn, AM, Press, MC, Phoenix, GK(2016)Nitrogen accumulation and partitioning in a High Arctic tundra ecosystem from extreme atmospheric N deposition events. Sci Total Environ 554-555 :303-10.
  13. Mitterer, V et al.(2016)Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation. Nat Commun 7 :10336.
  14. Blaud, A, Lerch, TZ, Phoenix, GK, Osborn, AM(2015)Arctic soil microbial diversity in a changing world. Res Microbiol 166 (10):796-813.
  15. Madru, C et al.(2015)Chaperoning 5S RNA assembly. Genes Dev 29 (13):1432-46.
  16. Tillault, AS et al.(2015)RNA size is a critical factor for U-containing substrate selectivity and permanent pseudouridylated product release during the RNA:Ψ-synthase reaction catalyzed by box H/ACA sRNP enzyme at high temperature. Biochimie 113 :134-42.
  17. Bourgeois, G, Chardon, F, Tillault, AS, Blaud, M(2015)Detection and labeling of small non-coding RNAs by splinted ligation. Methods Mol Biol 1296 :65-72.
  18. Loc'h, J et al.(2014)RNA mimicry by the fap7 adenylate kinase in ribosome biogenesis. PLoS Biol 12 (5):e1001860.
  19. Rothé, B et al.(2014)Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly. Nucleic Acids Res 42 (3):2015-36.
  20. Fourmann, JB et al.(2013)Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity. PLoS One 8 (7):e70313.
  21. Walbott, H et al.(2011)The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic. Genes Dev 25 (22):2398-408.
  22. Maenner, S et al.(2010)2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol 8 (1):e1000276.
  23. Alazard, R et al.(2005)Identification of the 'NORE' (N-Oct-3 responsive element), a novel structural motif and composite element. Nucleic Acids Res 33 (5):1513-23.
  24. Blaud, M et al.(2004)Characteristic patterns of N Oct-3 binding to a set of neuronal promoters. J Mol Biol 339 (5):1049-58.
  25. Blaud, M(1819)Observations and Cases Illustrating the Efficacy of Compressing the Carotid Arteries in Sanguineous Turgescence of the Cerebral Vessels. Med Chir J 1 (4):498-503.
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