Mme Marie-Isabelle Lannou » Equipe : Produits naturels, analyses et synthèses

Mme Marie-Isabelle Lannou

Chargée de Recherche CNRSCiTCoM
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Informations

Membre de l’équipe PNAS “Produits Naturels, Analyse et Synthèse” Pôle “Synthèse et Méthodes”

Recherche :

  • Chimie des Lanthanides (Sm, Ce, La, Nd, Pr) DEA et thèse
  • Synthèse totale de produits naturels d’intérêt biologique et d’analogues, ciblant le cancer (hémicalide, thapsigargine, salinosporamide A, discodermolide, sarcodictyines A and B), le diabète (FR225654) et le système nerveux central (vibsatine A and B)
  • Développement de méthodologies de synthèse en chimie organométallique (Ni, Au, Rh, Ru, Ti, Ag) et études méchanistiques associées (Ni, Ag)

 – Nouvel axe de recherche (2018) : Chimie verte (Ni) en milieu aqueux.

Publications sélectionnées :


36 documents

Articles dans une revue36 documents

  • Bao Yu, Selkti Mohamed, Janick Ardisson, Geoffroy Sorin, Marie-Isabelle Lannou. Silver oxide( i ) promoted Conia-ene/radical cyclization for a straightforward access to furan derivatives. Chemical Communications, 2022, 58 (9), pp.1374-1377. ⟨10.1039/D1CC06379K⟩. ⟨hal-03609400⟩
  • Bao Yu, Mohamed Selkti, Janick Ardisson, Marie-Isabelle Lannou, Geoffroy Sorin. Access to conjugated enynes via allenyl silver formation/cyclization/decarboxylation reaction catalyzed by silver carbonate(I). Organic Letters, 2022, 24 (31), pp.5721-5725. ⟨10.1021/acs.orglett.2c02142⟩. ⟨hal-03840749⟩
  • Bao Yu, Florent Bodinier, Maximiliene Saague‐tenefo, Patrice Gerardo, Janick Ardisson, et al.. One pot synthesis of α-amino nitrile units through alkylative Strecker cyanation from formamides. European Journal of Organic Chemistry, 2021, 2021 (25), pp.3634-3640. ⟨10.1002/ejoc.202100418⟩. ⟨hal-03366205⟩
  • Florent Bodinier, Youssouf Sanogo, Janick Ardisson, Marie-Isabelle Lannou, Geoffroy Sorin. Low-valent dialkoxytitanium(II): a useful tool for the synthesis of functionalized seven-membered ring compounds. Chemical Communications, 2021, 57 (29), pp.3603-3606. ⟨10.1039/d1cc00081k⟩. ⟨hal-03366094⟩
  • Luca Allievi, Sabrina Dhambri, Rongyu Sun, Mohamed Selkti, Marie-Isabelle Lannou, et al.. Gold(I)-catalyzed 7-exo-dig Cyclization: A Key Step to Access the Bicyclo[4.2.1]nonane Skeleton of Vibsatin A, a Neurotrophic Diterpenoid. Organic Letters, 2021, 23 (13), pp.5218-5222. ⟨10.1021/acs.orglett.1c01757⟩. ⟨hal-03366083⟩
  • Bao Yu, Anna Perfetto, Luca Allievi, Sabrina Dhambri, Marie‐noelle Rager, et al.. Silver(I) Oxide‐/DBU‐Promoted Synthesis of Dihydrofuran Units through Allenyl Silver Formation. Chemistry - A European Journal, In press, ⟨10.1002/chem.202002696⟩. ⟨hal-03044183⟩
  • Youssouf Sanogo, Raja Ben Othman, Sabrina Dhambri, Mohamed Selkti, Alan Jeuken, et al.. Ti(II) and Rh(I) Complexes as Reagents toward a Thapsigargin Core. Journal of Organic Chemistry, 2019, 84 (9), pp.5821-5830. ⟨10.1021/acs.joc.8b03249⟩. ⟨hal-02370403⟩
  • Camille Lecourt, Sabrina Dhambri, Khalil Yamani, Guillaume Boissonnat, Simon Specklin, et al.. Assembly of the Entire Carbon Backbone of a Stereoisomer of the Antitumor Marine Natural Product Hemicalide. Chemistry - A European Journal, 2019, 25 (11), pp.2745-2749. ⟨10.1002/chem.201806327⟩. ⟨hal-02379818⟩
  • C. Lecourt, S. Dhambri, L. Allievi, Y. Sanogo, N. Zeghbib, et al.. Natural products and ring-closing metathesis: synthesis of sterically congested olefins. Natural Product Reports, 2018, 35 (1), pp.105-124. ⟨10.1039/c7np00048k⟩. ⟨hal-02370500⟩
  • Camille Lecourt, Srikanth Boinapally, Sabrina Dhambri, Guillaume Boissonnat, Christophe Meyer, et al.. Elaboration of Sterically Hindered δ-Lactones through Ring-Closing Metathesis: Application to the Synthesis of the C1–C27 Fragment of Hemicalide. Journal of Organic Chemistry, 2016, 81 (24), pp.12275-12290. ⟨10.1021/acs.joc.6b02208⟩. ⟨hal-02370458⟩
  • Youssouf Sanogo, Luca Allievi, Camille Lecourt, Sabrina Dhambri, Janick Ardisson, et al.. Total syntheses of echinopines A and B, sesquiterpenes with a unique tetracyclic [3-5-5-7] skeleton. Tetrahedron, 2016, 72 (24), pp.3369-3377. ⟨10.1016/j.tet.2016.04.005⟩. ⟨hal-02370507⟩
  • Aurélien Tap, Camille Lecourt, Sabrina Dhambri, Mathieu Arnould, Gilles Galvani, et al.. Alkoxyallene-ynes: Selective Preparation of Bicyclo[5.3.0] Ring Systems Including a δ-Alkoxy Cyclopentadienone. Chemistry - A European Journal, 2016, 22 (14), pp.4938-4944. ⟨10.1002/chem.201504753⟩. ⟨hal-02370516⟩
  • Simon Specklin, Guillaume Boissonnat, Camille Lecourt, Geoffroy Sorin, Marie-Isabelle Lannou, et al.. Synthetic Studies toward the C32–C46 Segment of Hemicalide. Assignment of the Relative Configuration of the C36–C42 Subunit. Organic Letters, 2015, 17 (10), pp.2446-2449. ⟨10.1021/acs.orglett.5b00955⟩. ⟨hal-02370527⟩
  • S. Dhambri, S. Mohammad, O. Nguyen van Buu, G. Galvani, Y. Meyer, et al.. Recent advances in the synthesis of natural multifunctionalized decalins. Natural Product Reports, 2015, 32 (6), pp.841-864. ⟨10.1039/c4np00142g⟩. ⟨hal-02370535⟩
  • Geoffroy Sorin, Etienne Fleury, Christine Tran, Elise Prost, Nicolas Molinier, et al.. Synthetic Studies on Hemicalide: Development of a Convergent Approach toward the C1–C25 Fragment. Organic Letters, 2013, 15 (18), pp.4734-4737. ⟨10.1021/ol402077e⟩. ⟨hal-02370568⟩
  • Etienne Fleury, Geoffroy Sorin, Elise Prost, Ange Pancrazi, François Sautel, et al.. Relative Stereochemical Determination and Synthesis of the C17–C25 δ-Lactone Fragment of Hemicalide. Journal of Organic Chemistry, 2013, 78 (3), pp.855-864. ⟨10.1021/jo302440a⟩. ⟨hal-02370585⟩
  • Shabbair Mohammad, Sabrina Dhambri, Didier Gori, Carine Vaxelaire, Geoffroy Sorin, et al.. Asymmetric Sharpless Dihydroxylation Reaction of Chiral Bishomoallylic Alcohols: Application to the Synthesis of the C1–C10–C5 Fragment of FR225654. SYNLETT, 2013, 24 (19), pp.2581-2585. ⟨10.1055/s-0033-1340164⟩. ⟨hal-02370561⟩
  • Aurélien Tap, Morgan Jouanneau, Gilles Galvani, Geoffroy Sorin, Marie-Isabelle Lannou, et al.. Asymmetric synthesis of a highly functionalized enantioenriched system close to thapsigargin framework. Organic & Biomolecular Chemistry, 2012, 10 (40), pp.8140. ⟨10.1039/c2ob26194d⟩. ⟨hal-02370593⟩
  • Julien Barbion, Geoffroy Sorin, Mohamed Selkti, Esther Kellenberger, Rachid Baati, et al.. Stereoselective functionalization of pyrrolidinone moiety towards the synthesis of salinosporamide A. Tetrahedron, 2012, 68 (32), pp.6504-6512. ⟨10.1016/j.tet.2012.05.103⟩. ⟨hal-02370605⟩
  • Elsa De lemos, Evangelos Agouridas, Geoffroy Sorin, Antonio Guerreiro, Alain Commerçon, et al.. Conception, Synthesis, and Biological Evaluation of Original Discodermolide Analogues. Chemistry - A European Journal, 2011, 17 (36), pp.10123-10134. ⟨10.1002/chem.201100675⟩. ⟨hal-02370620⟩
  • Etienne Fleury, Marie-Isabelle Lannou, Olivia Bistri, François Sautel, Georges Massiot, et al.. Advances in the Universal NMR Database: Toward the Determination of the Relative Configurations of Large Polypropionates. European Journal of Organic Chemistry, 2009, 2009 (29), pp.4992-5001. ⟨10.1002/ejoc.200900616⟩. ⟨hal-02370630⟩
  • Etienne Fleury, Marie-Isabelle Lannou, Olivia Bistri, François Sautel, Georges Massiot, et al.. Relative Stereochemical Determination and Synthesis of the C1−C17 Fragment of a New Natural Polyketide. Journal of Organic Chemistry, 2009, 74 (18), pp.7034-7045. ⟨10.1021/jo9012833⟩. ⟨hal-02371106⟩
  • Carine Vaxelaire, Florence Souquet, Marie-Isabelle Lannou, Janick Ardisson, Jacques Royer. Anodic Oxidation: An Attractive Alternative to CAN-Mediated Cleavage of para -Methoxyphenyl Ethers. European Journal of Organic Chemistry, 2009, 2009 (19), pp.3138-3140. ⟨10.1002/ejoc.200900262⟩. ⟨hal-02371104⟩
  • Elsa De lemos, François-Hugues Porée, Arnaud Bourin, Julien Barbion, Evangelos Agouridas, et al.. Total Synthesis of Discodermolide: Optimization of the Effective Synthetic Route. Chemistry - A European Journal, 2008, 14 (35), pp.11092-11112. ⟨10.1002/chem.200801478⟩. ⟨hal-02371110⟩
  • Marie-Isabelle Lannou, Florence Hélion, Jean-Louis Namy. Applications of Lanthanide Trichloride Hydrates, Prepared from Mischmetall, in the Biginelli Reaction. SYNLETT, 2008, 2008 (1), pp.105-107. ⟨10.1055/s-2007-992387⟩. ⟨hal-02371229⟩
  • Marie-Isabelle Lannou, Florence Hélion, Jean-Louis Namy. Applications of Lanthanide Trichloride Hydrates Prepared from Mischmetall in Luche-Type Reduction. SYNLETT, 2007, 2007 (17), pp.2707-2710. ⟨10.1055/s-2007-991062⟩. ⟨hal-02371227⟩
  • Anne Seggio, Marie-Isabelle Lannou, Floris Chevallier, Daisuke Nobuto, Masanobu Uchiyama, et al.. Ligand-Activated Lithium-Mediated Zincation of N-Phenylpyrrole. Chemistry - A European Journal, 2007, 13 (35), pp.9982-9989. ⟨10.1002/chem.200700608⟩. ⟨hal-00782331⟩
  • Anne Seggio, Marie-Isabelle Lannou, Floris Chevallier, Daisuke Nobuto, Masanobu Uchiyama, et al.. Ligand-Activated Lithium-Mediated Zincation of N-Phenylpyrrole. Chemistry - A European Journal, 2007, 13 (35), pp.9982-9989. ⟨10.1002/chem.200700608⟩. ⟨hal-02371118⟩
  • Sylvie Dhulut, Arnaud Bourin, Marie-Isabelle Lannou, Etienne Fleury, Nathalie Lensen, et al.. Cyclic Allyl Carbamates in Stereoselectivesyn SE′ Processes: Synthetic Approach to Sarcodictyins and Eleutherobin. European Journal of Organic Chemistry, 2007, 2007 (31), pp.5235-5243. ⟨10.1002/ejoc.200700490⟩. ⟨hal-02371125⟩
  • Dieter Enders, Alexandre Saint-Dizier, Marie-Isabelle Lannou, Achim Lenzen. The Phospha-Michael Addition in Organic Synthesis. European Journal of Organic Chemistry, 2006, 2006 (1), pp.29-49. ⟨10.1002/ejoc.200500593⟩. ⟨hal-02371130⟩
  • Dieter Enders, Achim Lenzen, Michael Backes, Carsten Janeck, Kelly Catlin, et al.. Asymmetric Total Synthesis of the 1- e pi -Aglycon of the Cripowellins A and B. Journal of Organic Chemistry, 2005, 70 (25), pp.10538-10551. ⟨10.1021/jo0518093⟩. ⟨hal-02371135⟩
  • Marie-Isabelle Lannou, Florence Hélion, Jean-Louis Namy. Some uses of mischmetall in organic synthesis. Tetrahedron, 2003, 59 (52), pp.10551-10565. ⟨10.1016/j.tet.2003.07.017⟩. ⟨hal-02371191⟩
  • Florence Hélion, Marie-Isabelle Lannou, Jean-Louis Namy. A new preparation of samarium dibromide and its use in stoichiometric and catalytic pinacol coupling reactions. Tetrahedron Letters, 2003, 44 (29), pp.5507-5510. ⟨10.1016/S0040-4039(03)01229-2⟩. ⟨hal-02371184⟩
  • Marie-Isabelle Lannou, Florence Hélion, Jean-Louis Namy. Catalytic Barbier-type reactions of lactones and esters mediated by the Mischmetall/SmI2(cat.) system or the Mischmetall/[SmI2/NiI2(cat′.)](cat.) system. Tetrahedron Letters, 2002, 43 (45), pp.8007-8010. ⟨10.1016/S0040-4039(02)01979-2⟩. ⟨hal-02371179⟩
  • Aurore di Scala, Stefania Garbacia, Florence Hélion, Marie-Isabelle Lannou, Jean-Louis Namy. Barbier/Grignard-Type Allylation or Benzylation Mediated by the Mischmetall/SmI2(cat.) System. European Journal of Organic Chemistry, 2002, 2002 (17), pp.2989-2995. <a target="_blank" href="https://dx.doi.org/10.1002/1099-0690(200209)2002:173.0.CO;2-0">⟨10.1002/1099-0690(200209)2002:173.0.CO;2-0⟩. ⟨hal-02371166⟩
  • Jacqueline Collin, Nada Jaber, Marie Isabelle Lannou. Imino-Diels–Alder and imino-aldol reactions catalyzed by samarium diiodide. Tetrahedron Letters, 2001, 42 (42), pp.7405-7407. ⟨10.1016/S0040-4039(01)01581-7⟩. ⟨hal-02371145⟩

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