Mme Nathalie Chamond

Researcher CNRSCiTCoM
Tel :: Number

Biographical Info

Research :

Structural study of viral RNAs by SHAPE

Molecular dissection of IRES-mediated translation initiation

Molecular mechanism of the RNA helicase, DDX3X

Role(s) of DDX3X in HIV-1 translation initiation

Expertise :

Molecular biology

Biochemistry

Cellular biology

Parasitology




28 documents

Journal articles

  • Jenniffer Angulo, C. Joaquín Cáceres, Nataly Contreras, Leandro Fernández-García, Nathalie Chamond, et al.. Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site. Viruses, 2023, 15 (1), pp.8. ⟨10.3390/v15010008⟩. ⟨hal-04275415⟩
  • Grégoire de Bisschop, Melissa Ameur, Nathalie Ulryck, Fatima Benattia, Luc Ponchon, et al.. HIV-1 gRNA, a biological substrate, uncovers the potency of DDX3X biochemical activity. Biochimie, 2019, 164, pp.83-94. ⟨10.1016/j.biochi.2019.03.008⟩. ⟨hal-02325540⟩
  • Margaret Willcocks, Salmah Zaini, Nathalie Chamond, Nathalie Ulryck, Delphine M Allouche, et al.. Distinct roles for the IIId2 sub-domain in pestivirus and picornavirus internal ribosome entry sites. Nucleic Acids Research, 2017, 45 (22), pp.13016-13028. ⟨10.1093/nar/gkx991⟩. ⟨hal-02523078⟩
  • Jules Deforges, Sylvain de Breyne, Melissa Ameur, Nathalie Ulryck, Nathalie Chamond, et al.. Two ribosome recruitment sites direct multiple translation events within HIV1 Gag open reading frame. Nucleic Acids Research, 2017, 45 (12), pp.7382--7400. ⟨10.1093/nar/gkx303⟩. ⟨hal-01505282⟩
  • Jenniffer Angulo, Nathalie Ulryck, Jules Deforges, Nathalie Chamond, Marcelo López-Lastra, et al.. LOOP IIId of the HCV IRES is essential for the structural rearrangement of the 40S-HCV IRES complex. Nucleic Acids Research, 2016, 44 (3), pp.1309-1325. ⟨10.1093/nar/gkv1325⟩. ⟨hal-02523090⟩
  • Nathalie Chamond, Jules Deforges, Nathalie Ulryck, Bruno Sargueil. 40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of Type II IRESs.. Nucleic Acids Research, 2014, 42 (16), pp.10373-84. ⟨10.1093/nar/gku720⟩. ⟨hal-01067767⟩
  • Nathalie Chamond, Jules Deforges, Nathalie Ulryck, Bruno Sargueil. 40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of Type II IRESs. Nucleic Acids Research, 2014, 42, pp.10373 - 10384. ⟨10.1093/nar/gku720⟩. ⟨hal-01075147⟩
  • Amira Souii, Manel M'Hadheb-Gharbi, Bruno Sargueil, Audrey Brossard, Nathalie Chamond, et al.. Ribosomal Initiation Complex Assembly within the Wild-Strain of Coxsackievirus B3 and Live-Attenuated Sabin3-like IRESes during the Initiation of Translation. International Journal of Molecular Sciences, 2013, 14 (3), pp.4400-4418. ⟨10.3390/ijms14034400⟩. ⟨hal-02523097⟩
  • Armand Berneman, Lory Montout, Sophie Goyard, Nathalie Chamond, Alain Cosson, et al.. Combined approaches for drug design points the way to novel proline racemase inhibitor candidates to fight Chagas' disease.. PLoS ONE, 2013, 8 (4), pp.e60955. ⟨10.1371/journal.pone.0060955⟩. ⟨hal-00833388⟩
  • Sylvain de Breyne, Nathalie Chamond, Didier Décimo, Mary-Anne Trabaud, Patrice André, et al.. In vitro studies reveal that different modes of initiation on HIV-1 mRNA have different levels of requirement for eukaryotic initiation factor 4F.. FEBS Journal, 2012, 279 (17), pp.3098-111. ⟨10.1111/j.1742-4658.2012.08689.x⟩. ⟨hal-00965629⟩
  • Jules Deforges, Nathalie Chamond, Bruno Sargueil. Structural investigation of HIV-1 genomic RNA dimerization process reveals a role for the Major Splice-site Donor stem loop. Biochimie, 2012, 94 (7), pp.1481-1489. ⟨10.1016/j.biochi.2012.02.009⟩. ⟨hal-02544383⟩
  • Simon d'Archivio, Mathieu Medina, Alain Cosson, Nathalie Chamond, Brice Rotureau, et al.. Genetic engineering of Trypanosoma (Dutonella) vivax and in vitro differentiation under axenic conditions.. PLoS Neglected Tropical Diseases, 2011, 5 (12), pp.e1461. ⟨10.1371/journal.pntd.0001461⟩. ⟨pasteur-01371319⟩
  • Nicolas Locker, Nathalie Chamond, Bruno Sargueil. A conserved structure within the HIV gag open reading frame that controls translation initiation directly recruits the 40S subunit and eIF3. Nucleic Acids Research, 2011, 39 (6), pp.2367-2377. ⟨10.1093/nar/gkq1118⟩. ⟨hal-02544362⟩
  • Nathalie Chamond, Nicolas Locker, Bruno Sargueil. The different pathways of HIV genomic RNA translation. Biochemical Society Transactions, 2010, 38 (6), pp.1548-1552. ⟨10.1042/BST0381548⟩. ⟨hal-02544365⟩
  • Laure Weill, Laurie James, Nathalie Ulryck, Nathalie Chamond, Cecile Herbreteau, et al.. A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA. Nucleic Acids Research, 2010, 38 (4), pp.1367-1381. ⟨10.1093/nar/gkp1109⟩. ⟨hal-02544350⟩
  • Marie Christine Blom-Potar, Nathalie Chamond, Alain Cosson, Grégory Jouvion, Sabrina Droin-Bergère, et al.. Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. II. Immunobiological dysfunctions. PLoS Neglected Tropical Diseases, 2010, 4 (8), pp.e793. ⟨10.1371/journal.pntd.0000793⟩. ⟨hal-02544359⟩
  • Nathalie Chamond, Alain Cosson, Marie Christine Blom-Potar, Grégory Jouvion, Simon d'Archivio, et al.. Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters. PLoS Neglected Tropical Diseases, 2010, 4 (8), pp.e792. ⟨10.1371/journal.pntd.0000792⟩. ⟨hal-02544358⟩
  • Huafang Shi, Nathalie Chamond, Appolinaire Djikeng, Christian Tschudi, Elisabetta Ullu. RNA Interference in Trypanosoma brucei. Journal of Biological Chemistry, 2009, 284 (52), pp.36511-36520. ⟨10.1074/jbc.M109.073072⟩. ⟨hal-02544342⟩
  • Nathalie Chamond, Alain Cosson, Nicolas Coatnoan, Paola Minoprio. Proline racemases are conserved mitogens: characterization of a Trypanosoma vivax proline racemase. Molecular and Biochemical Parasitology, 2009, 165 (2), pp.170-179. ⟨10.1016/j.molbiopara.2009.02.002⟩. ⟨hal-02544235⟩
  • Nicolas Coatnoan, Armand Berneman, Nathalie Chamond, Paola Minoprio. Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline. Memórias do Instituto Oswaldo Cruz, 2009, 104 (suppl 1), pp.295-300. ⟨10.1590/s0074-02762009000900039⟩. ⟨hal-02544244⟩
  • Maira Goytia, Nathalie Chamond, Alain Cosson, Nicolas Coatnoan, Daniel Hermand, et al.. Molecular and Structural Discrimination of Proline Racemase and Hydroxyproline-2-Epimerase from Nosocomial and Bacterial Pathogens. PLoS ONE, 2007, 2 (9), pp.e885. ⟨10.1371/journal.pone.0000885⟩. ⟨hal-02523217⟩
  • Alejandro Buschiazzo, Maira Goytia, Francis Schaeffer, Wim M. Degrave, William Shepard, et al.. Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase. Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩. ⟨hal-02523212⟩
  • Huafang Shi, Djikeng Appolinaire, Nathalie Chamond, Huan Ngô, Christian Tschudi, et al.. Repression of gene expression by the coliphage MS2 coat protein in Trypanosoma brucei. Molecular and Biochemical Parasitology, 2005, 144 (1), pp.119-122. ⟨10.1016/j.molbiopara.2005.07.005⟩. ⟨hal-02523203⟩
  • Nathalie Chamond, Maira Goytia, Nicolas Coatnoan, Jean Christophe Barale, Alain Cosson, et al.. Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity.. Molecular Microbiology, 2005, 58 (1), pp.46-60. ⟨10.1111/j.1365-2958.2005.04808.x⟩. ⟨hal-00126978⟩
  • Huafang Shi, Nathalie Chamond, Christian Tschudi, Elisabetta Ullu. Selection and Characterization of RNA Interference-Deficient Trypanosomes Impaired in Target mRNA Degradation. Eukaryotic Cell, 2004, 3 (6), pp.1445-1453. ⟨10.1128/EC.3.6.1445-1453.2004⟩. ⟨hal-02523198⟩
  • Nathalie Chamond, Christophe Grégoire, Nicolas Coatnoan, Catherine Rougeot, Lucio H Freitas-Junior, et al.. Biochemical Characterization of Proline Racemases from the Human Protozoan Parasite Trypanosoma cruzi and Definition of Putative Protein Signatures. Journal of Biological Chemistry, 2003, 278 (18), pp.15484-15494. ⟨10.1074/jbc.m210830200⟩. ⟨hal-02523188⟩
  • Nathalie Chamond, Nicolas Coatnoan, Paola Minoprio. Immunotherapy of Trypanosoma Cruzi Infections. Current Drug Targets, 2002, 2 (3), pp.247-254. ⟨10.2174/1568008023340604⟩. ⟨hal-02523178⟩
  • Bernardo Reina-San-Martin, Wim M. Degrave, Catherine Rougeot, Alain Cosson, Nathalie Chamond, et al.. A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase. Nature Medicine, 2000, 6 (8), pp.890-897. ⟨10.1038/78651⟩. ⟨hal-02523150⟩