Mme Martine Largeron

Directrice de recherche CNRSCiTCoM
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106 documents

Articles dans une revue

  • Anne Neudorffer, Patrick Deschamps, Martine Largeron, Brigitte Deguin. An electrochemical access to 2-amino-2,3-dihydro-1,4-benzodioxanes derived from hydroxytyrosol. Organic & Biomolecular Chemistry, 2024, 22 (5), pp.1057-1063. ⟨10.1039/d3ob01858j⟩. ⟨hal-04438018⟩
  • Anne Neudorffer, Patrick Deschamps, Martine Largeron, Brigitte Deguin. An electrochemical access to 2-amino-2,3-dihydro-1,4-benzodioxanes derived from hydroxytyrosol. Organic & Biomolecular Chemistry, 2024, 22 (5), pp.1057-1063. ⟨10.1039/d3ob01858j⟩. ⟨hal-04586320⟩
  • Martine Largeron. Aerobic catalytic systems inspired by copper amine oxidases. Pure and Applied Chemistry, 2020, 92 (2), pp.233-242. ⟨10.1515/pac-2019-0107⟩. ⟨hal-02995177⟩
  • Martine Largeron, Patrick Deschamps, Karim Hammad, Maurice-Bernard Fleury. A dual biomimetic process for the selective aerobic oxidative coupling of primary amines using pyrogallol as a precatalyst. Isolation of the [5 + 2] cycloaddition redox intermediates. Green Chemistry, 2020, 22 (6), pp.1894-1905. ⟨10.1039/c9gc03992a⟩. ⟨hal-02491888⟩
  • Martine Largeron, Khac Minh Huy Nguyen. Recent Advances in the Synthesis of Benzimidazole Derivatives from the Oxidative Coupling of Primary Amines. Synthesis: Journal of Synthetic Organic Chemistry, 2018, 50 (02), pp.241-253. ⟨10.1055/s-0036-1590915⟩. ⟨hal-02384557⟩
  • Martine Largeron, Maurice-Bernard Fleury. A Bioinspired Organocatalytic Cascade for the Selective Oxidation of Amines under Air. Chemistry - A European Journal, 2017, 23 (28), pp.6763-6767. ⟨10.1002/chem.201701402⟩. ⟨hal-02384567⟩
  • Martine Largeron. Inside front cover. Organic & Biomolecular Chemistry, 2017, 15 (22), pp.4714-4714. ⟨10.1039/C7OB90094E⟩. ⟨hal-02397124⟩
  • Martine Largeron. Aerobic catalytic systems inspired by copper amine oxidases: recent developments and synthetic applications. Organic & Biomolecular Chemistry, 2017, 15 (22), pp.4722-4730. ⟨10.1039/c7ob00507e⟩. ⟨hal-02384644⟩
  • Khac Minh Huy Nguyen, Martine Largeron. ChemInform Abstract: Catalytic Oxidative Coupling of Primary Amines under Air: A Flexible Route to Benzimidazole Derivatives.. ChemInform, 2016, 47 (26), ⟨10.1002/chin.201626151⟩. ⟨hal-02396968⟩
  • Khac Minh Huy Nguyen, Martine Largeron. Catalytic Oxidative Coupling of Primary Amines under Air: A Flexible Route to Benzimidazole Derivatives. European Journal of Organic Chemistry, 2016, 2016 (5), pp.1025-1032. ⟨10.1002/ejoc.201501520⟩. ⟨hal-02384649⟩
  • Khac Minh Huy Nguyen, Martine Largeron. ChemInform Abstract: A Bioinspired Catalytic Aerobic Oxidative C-H Functionalization of Primary Aliphatic Amines: Synthesis of 1,2-Disubstituted Benzimidazoles.. ChemInform, 2016, 47 (2), ⟨10.1002/chin.201602120⟩. ⟨hal-02396963⟩
  • Khac Minh Huy Nguyen, Martine Largeron. A Bioinspired Catalytic Aerobic Oxidative C-H Functionalization of Primary Aliphatic Amines: Synthesis of 1,2-Disubstituted Benzimidazoles. Chemistry - A European Journal, 2015, 21 (36), pp.12606-12610. ⟨10.1002/chem.201502487⟩. ⟨hal-02384771⟩
  • Kevin Cottet, Anne Neudörffer, Marina Kritsanida, Sylvie Michel, Marie-Christine Lallemand, et al.. Polycyclic Polyprenylated Xanthones from Symphonia globulifera : Isolation and Biomimetic Electrosynthesis. Journal of Natural Products, 2015, 78 (8), pp.2136-2140. ⟨10.1021/acs.jnatprod.5b00239⟩. ⟨hal-02384687⟩
  • Martine Largeron, Maurice-Bernard Fleury. ChemInform Abstract: A Metalloenzyme-Like Catalytic System for the Chemoselective Oxidative Cross-Coupling of Primary Amines to Imines under Ambient Conditions.. ChemInform, 2015, 46 (29), pp.no-no. ⟨10.1002/chin.201529104⟩. ⟨hal-02396971⟩
  • Khac Minh Huy Nguyen, Leslie Schwendimann, Pierre Gressens, Martine Largeron. ChemInform Abstract: Regiospecific Synthesis of Neuroprotective 1,4-Benzoxazine Derivatives Through a Tandem Oxidation-Diels-Alder Reaction.. ChemInform, 2015, 46 (29), pp.no-no. ⟨10.1002/chin.201529226⟩. ⟨hal-02396973⟩
  • Martine Largeron, Maurice-Bernard Fleury. A Metalloenzyme-Like Catalytic System for the Chemoselective Oxidative Cross-Coupling of Primary Amines to Imines under Ambient Conditions. Chemistry - A European Journal, 2015, 21 (9), pp.3815-3820. ⟨10.1002/chem.201405843⟩. ⟨hal-02384694⟩
  • Khac Minh Huy Nguyen, Leslie Schwendimann, Pierre Gressens, Martine Largeron. Regiospecific synthesis of neuroprotective 1,4-benzoxazine derivatives through a tandem oxidation–Diels–Alder reaction. Organic & Biomolecular Chemistry, 2015, 13 (12), pp.3749-3756. ⟨10.1039/c5ob00049a⟩. ⟨hal-02384706⟩
  • Martine Largeron. ChemInform Abstract: Protocols for the Catalytic Oxidation of Primary Amines to Imines. ChemInform, 2013, 44 (44), pp.no-no. ⟨10.1002/chin.201344239⟩. ⟨hal-02396978⟩
  • Martine Largeron. Protocols for the Catalytic Oxidation of Primary Amines to Imines. European Journal of Organic Chemistry, 2013, 2013 (24), pp.5225-5235. ⟨10.1002/ejoc.201300315⟩. ⟨hal-02384718⟩
  • Martine Largeron, Maurice-Bernard Fleury. Bioinspired Oxidation Catalysts. Science, 2013, 339 (6115), pp.43-44. ⟨10.1126/science.1232220⟩. ⟨hal-02384736⟩
  • Martine Largeron, Maurice-Bernard Fleury. ChemInform Abstract: A Biologically Inspired Cu(I)/Topaquinone-Like Co-Catalytic System for the Highly Atom-Economical Aerobic Oxidation of Primary Amines to Imines.. ChemInform, 2012, 43 (41), pp.no-no. ⟨10.1002/chin.201241064⟩. ⟨hal-02396982⟩
  • Martine Largeron, Maurice-Bernard Fleury. A Biologically Inspired Cu I /Topaquinone-Like Co-Catalytic System for the Highly Atom-Economical Aerobic Oxidation of Primary Amines to Imines. Angewandte Chemie International Edition, 2012, 51 (22), pp.5409-5412. ⟨10.1002/anie.201200587⟩. ⟨hal-02384814⟩
  • Claire-Marie Martinez, Anne Neudörffer, Martine Largeron. A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA (“ecstasy”) from R-(−)- and S-(+)-N-methyl-α-methyldopamine precursors. Organic & Biomolecular Chemistry, 2012, 10 (18), pp.3739. ⟨10.1039/c2ob25245g⟩. ⟨hal-02384807⟩
  • Anne Neudörffer, Melanie Mueller, Claire-Marie Martinez, Annis Mechan, Una Mccann, et al.. Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and Its 6-( N -Acetylcystein- S -yl) Conjugate. Chemical Research in Toxicology, 2011, 24 (6), pp.968-978. ⟨10.1021/tx2001459⟩. ⟨hal-02384825⟩
  • Martine Largeron. Amine oxidases of the quinoproteins family: Their implication in the metabolic oxidation of xenobiotics. Annales Pharmaceutiques Françaises, 2011, 69 (1), pp.53-61. ⟨10.1016/j.pharma.2010.10.002⟩. ⟨hal-02384856⟩
  • Anne Felim, Guadalupe Herrera, Anne Neudörffer, Manuel Blanco, José-Enrique O’connor, et al.. Synthesis and in Vitro Cytotoxicity Profile of the R -Enantiomer of 3,4-Dihydroxymethamphetamine ( R -(−)-HHMA): Comparison with Related Catecholamines. Chemical Research in Toxicology, 2010, 23 (1), pp.211-219. ⟨10.1021/tx9003374⟩. ⟨hal-02384869⟩
  • Martine Largeron, Maurice-Bernard Fleury, Margherita Strolin Benedetti. A small molecule that mimics the metabolic activity of copper-containing amine oxidases (CuAOs) toward physiological mono- and polyamines. Organic & Biomolecular Chemistry, 2010, 8 (16), pp.3796. ⟨10.1039/c004501b⟩. ⟨hal-02384876⟩
  • Melanie Mueller, Jie Yuan, Anne Felim, Anne Neudörffer, Frank Peters, et al.. Further Studies on the Role of Metabolites in (±)-3,4-Methylenedioxymethamphetamine-Induced Serotonergic Neurotoxicity. Drug Metabolism and Disposition, 2009, 37 (10), pp.2079-2086. ⟨10.1124/dmd.109.028340⟩. ⟨hal-02384917⟩
  • Martine Largeron. A one-pot chemoselective synthesis of secondary amines by using a biomimetic electrocatalytic system. Electrochimica Acta, 2009, 54 (22), pp.5109-5115. ⟨10.1016/j.electacta.2009.01.005⟩. ⟨hal-02384927⟩
  • Martine Largeron, Maurice-Bernard Fleury. ChemInform Abstract: A Biomimetic Electrocatalytic System for the Atom-Economical Chemoselective Synthesis of Secondary Amines.. ChemInform, 2009, 40 (25), ⟨10.1002/chin.200925046⟩. ⟨hal-02397074⟩
  • M.-B. Fleury, A. Neudörffer, A. Felim, M. Blanco, F.-P. Monnet, et al.. Métabolites de l’ecstasy et phénomènes de cytotoxicité. Annales Pharmaceutiques Françaises, 2009, 67 (2), pp.91-96. ⟨10.1016/j.pharma.2008.12.002⟩. ⟨hal-02385038⟩
  • Martine Largeron, Maurice-Bernard Fleury. A Biomimetic Electrocatalytic System for the Atom-Economical Chemoselective Synthesis of Secondary Amines. Organic Letters, 2009, 11 (4), pp.883-886. ⟨10.1021/ol802885b⟩. ⟨hal-02384938⟩
  • Martine Largeron, Angèle Chiaroni, Maurice-Bernard Fleury. ChemInform Abstract: Environmentally Friendly Chemoselective Oxidation of Primary Aliphatic Amines by Using a Biomimetic Electrocatalytic System.. ChemInform, 2008, 39 (21), ⟨10.1002/chin.200821074⟩. ⟨hal-02397075⟩
  • Martine Largeron, Angèle Chiaroni, Maurice-Bernard Fleury. Environmentally Friendly Chemoselective Oxidation of Primary Aliphatic Amines by Using a Biomimetic Electrocatalytic System. Chemistry - A European Journal, 2008, 14 (3), pp.996-1003. ⟨10.1002/chem.200700876⟩. ⟨hal-02384952⟩
  • Anne Felim, Anne Neudorffer, François P. Monnet, Martine Largeron. Environmentally friendly expeditious one-pot electrochemical synthesis of bis-catechol-thioether metabolites of ecstasy: in vitro neurotoxic effects in the rat hippocampus. International Journal of Electrochemical Science, 2008, 3 (2), pp.266-281. ⟨hal-03138868⟩
  • Anne Felim, Amparo Urios, Anne Neudörffer, Guadalupe Herrera, Manuel Blanco, et al.. Bacterial Plate Assays and Electrochemical Methods: An Efficient Tandem for Evaluating the Ability of Catechol−Thioether Metabolites of MDMA (“Ecstasy”) to Induce Toxic Effects through Redox-Cycling. Chemical Research in Toxicology, 2007, 20 (4), pp.685-693. ⟨10.1021/tx6003584⟩. ⟨hal-02384959⟩
  • Anne Neudörffer, Maurice-Bernard Fleury, Jean-Pierre Desvergne, Martine Largeron. Effects of lithium ion-pairing on the electrochemical oxidation of 4-hydroxycinnamate derivatives. Electrochimica Acta, 2006, 52 (2), pp.715-722. ⟨10.1016/j.electacta.2006.06.001⟩. ⟨hal-02384964⟩
  • Amparo Urios, Martine Largeron, Maurice-Bernard Fleury, Manuel Blanco. A convenient approach for evaluating the toxicity profiles of in vitro neuroprotective alkylaminophenol derivatives. Free Radical Biology and Medicine, 2006, 40 (5), pp.791-800. ⟨10.1016/j.freeradbiomed.2005.10.001⟩. ⟨hal-02384992⟩
  • Anne Neudörffer, Jean-Pierre Desvergne, Dominique Bonnefont-Rousselot, Alain Legrand, Maurice-Bernard Fleury, et al.. Protective Effects of 4-Hydroxycinnamic Ethyl Ester Derivatives and Related Dehydrodimers against Oxidation of LDL: Radical Scavengers or Metal Chelators?. Journal of Agricultural and Food Chemistry, 2006, 54 (5), pp.1898-1905. ⟨10.1021/jf052923p⟩. ⟨hal-02384987⟩
  • Daiwang Xu, Angèle Chiaroni, Maurice-Bernard Fleury, Martine Largeron. Electrochemically Induced Cascade Reaction for the Assembly of Libraries of Biologically Relevant 1,4-Benzoxazine Derivatives. Journal of Organic Chemistry, 2006, 71 (17), pp.6374-6381. ⟨10.1021/jo060452f⟩. ⟨hal-02384975⟩
  • Daiwang Xu, Angèle Chiaroni, Martine Largeron. A One-Pot Regiospecific Synthesis of Highly Functionalized 1,4-Benzodioxin Derivatives from an Electrochemically Induced Diels−Alder Reaction. Organic Letters, 2005, 7 (23), pp.5273-5276. ⟨10.1021/ol052146e⟩. ⟨hal-02384997⟩
  • Estelle Blattes, Maurice-Bernard Fleury, Martine Largeron. Simultaneously electrogenerated diene and dienophile: A unique access to novel polyfunctionalized 1,4-benzoxazine derivatives as neuroprotective agents. Electrochimica Acta, 2005, 50 (25-26), pp.4902-4910. ⟨10.1016/j.electacta.2004.12.051⟩. ⟨hal-02385009⟩
  • Estelle Blattes, Brian Lockhart, Pierre Lestage, Leslie Schwendimann, Pierre Gressens, et al.. Novel 2-Alkylamino-1,4-benzoxazine Derivatives as Potent Neuroprotective Agents: Structure−Activity Relationship Studies. Journal of Medicinal Chemistry, 2005, 48 (4), pp.1282-1286. ⟨10.1021/jm040874m⟩. ⟨hal-02385014⟩
  • Anne Neudörffer, Dominique Bonnefont-Rousselot, Alain Legrand, Maurice-Bernard Fleury, Martine Largeron. 4-Hydroxycinnamic Ethyl Ester Derivatives and Related Dehydrodimers: Relationship between Oxidation Potential and Protective Effects against Oxidation of Low-Density Lipoproteins. Journal of Agricultural and Food Chemistry, 2004, 52 (7), pp.2084-2091. ⟨10.1021/jf035068n⟩. ⟨hal-02385024⟩
  • Estelle Blattes, Maurice-Bernard Fleury, Martine Largeron. Simultaneously Electrogenerated Cycloaddition Partners for Regiospecific Inverse-Electron-Demand Diels−Alder Reactions: A Route for Polyfunctionalized 1,4-Benzoxazine Derivatives. Journal of Organic Chemistry, 2004, 69 (3), pp.882-890. ⟨10.1021/jo035614b⟩. ⟨hal-02385054⟩
  • Anne Neudorffer, Brigitte Deguin, Céline Hamel, Maurice-Bernard Fleury, Martine Largeron. Electrochemical Oxidative Coupling of 4-Hydroxycinnamic Ester Derivatives: A Convenient Methodology for the Biomimetic Synthesis of Lignin Precursors. Collection of Czechoslovak Chemical Communications, 2003, 68 (8), pp.1515-1530. ⟨10.1135/cccc20031515⟩. ⟨hal-02385078⟩
  • Martine Largeron, Anne Neudörffer, Maurice-Bernard Fleury. Oxidation of Unactivated Primary Aliphatic Amines Catalyzed by an Electrogenerated 3,4-Azaquinone Species: A Small-Molecule Mimic of Amine Oxidases. Angewandte Chemie International Edition, 2003, 42 (9), pp.1026-1029. ⟨10.1002/anie.200390263⟩. ⟨hal-02385072⟩
  • Martine Largeron, Anne Neudorffer, Marc Vuilhorgne, Estelle Blattes, Maurice-Bernard Fleury. ChemInform Abstract: Regiospecific Inverse-Electron-Demand Diels-Alder Reaction of Simultaneously Electrogenerated Diene and Dienophile: An Expeditious Route to Polyfunctionalized 1,4-Benzoxazine Derivatives.. ChemInform, 2002, 33 (30), pp.no-no. ⟨10.1002/chin.200230196⟩. ⟨hal-02397073⟩
  • Martine Largeron, Anne Neudorffer, Marc Vuilhorgne, Estelle Blattes, Maurice-Bernard Fleury. Regiospecific Inverse-Electron-Demand Diels–Alder Reaction of Simultaneously Electrogenerated Diene and Dienophile: An Expeditious Route to Polyfunctionalized 1,4-Benzoxazine Derivatives. Angewandte Chemie International Edition, 2002, 41 (5), pp.824. <a target="_blank" href="https://dx.doi.org/10.1002/1521-3773(20020301)41:53.0.co;2-z">⟨10.1002/1521-3773(20020301)41:53.0.co;2-z⟩. ⟨hal-02385108⟩
  • Martine Largeron, Bettina Mesples, Pierre Gressens, Roméo Cecchelli, Michael Spedding, et al.. The neuroprotective activity of 8-alkylamino-1,4-benzoxazine antioxidants. European Journal of Pharmacology, 2001, 424 (3), pp.189-194. ⟨10.1016/S0014-2999(01)01152-9⟩. ⟨hal-02385117⟩
  • Martine Largeron, Brid Farrell, Jean-François Rousseau, Maurice-Bernard Fleury, Pierre Potier, et al.. ChemInform Abstract: Efficient Electrochemical Cleavage of N,N-Dimethylaminosulfonyl-Protected Indoles.. ChemInform, 2001, 32 (9), pp.no-no. ⟨10.1002/chin.200109117⟩. ⟨hal-02397014⟩
  • Nicolas Auzeil, Alain Tomas, Maurice-Bernard Fleury, Martine Largeron. ChemInform Abstract: First N-Alkyl Heterolysis of Tertiary Benzamides in Neutral Conditions.. ChemInform, 2001, 32 (9), pp.no-no. ⟨10.1002/chin.200109084⟩. ⟨hal-02397012⟩
  • Martine Largeron, Bettina Mesples, Pierre Gressens, Roméo Cecchelli, Michael Spedding, et al.. The neuroprotective activity of 8-alkylamino-1, 4-benzoxazine antioxidants. European Journal of Pharmacology, 2001, 424, p. 189-194. ⟨hal-00535639⟩
  • Martine Largeron, Maurice-Bernard Fleury. Oxidative Deamination of Benzylamine by Electrogenerated Quinonoid Systems as Mimics of Amine Oxidoreductases Cofactors. Journal of Organic Chemistry, 2000, 65 (26), pp.8874-8881. ⟨10.1021/jo000478l⟩. ⟨hal-02385121⟩
  • Martine Largeron, Brid Farrell, Jean-François Rousseau, Maurice-Bernard Fleury, Pierre Potier, et al.. Efficient electrochemical cleavage of N,N-dimethylaminosulfonyl-protected indoles. Tetrahedron Letters, 2000, 41 (49), pp.9403-9406. ⟨10.1016/S0040-4039(00)01504-5⟩. ⟨hal-02385127⟩
  • Nicolas Auzeil, Alain Tomas, Maurice-Bernard Fleury, Martine Largeron. First N-alkyl heterolysis of tertiary benzamides in neutral conditions. Tetrahedron Letters, 2000, 41 (45), pp.8781-8785. ⟨10.1016/S0040-4039(00)01555-0⟩. ⟨hal-02385132⟩
  • Ronan Larget, Brian Lockhart, Pierre Renard, Martine Largeron. ChemInform Abstract: A Convenient Extension of the Wessely-Moser Rearrangement for the Synthesis of Substituted Alkylaminoflavones as Neuroprotective Agents in vitro.. ChemInform, 2000, 31 (30), pp.no-no. ⟨10.1002/chin.200030120⟩. ⟨hal-02397006⟩
  • Ronan Larget, Brian Lockhart, Pierre Renard, Martine Largeron. A convenient extension of the Wessely–Moser rearrangement for the synthesis of substituted alkylaminoflavones as neuroprotective agents in vitro. Bioorganic and Medicinal Chemistry Letters, 2000, 10 (8), pp.835-838. ⟨10.1016/S0960-894X(00)00110-4⟩. ⟨hal-02385135⟩
  • Ronan Larget, Brian Lockhart, Bruno Pfeiffer, Anne Neudorffer, Maurice-Bernard Fleury, et al.. ChemInform Abstract: Synthesis of Novel Orthoalkylaminophenol Derivatives as Potent Neuroprotective Agents in vitro.. ChemInform, 2000, 31 (7), pp.no-no. ⟨10.1002/chin.200007083⟩. ⟨hal-02397003⟩
  • Martine Largeron, Brian Lockhart, Bruno Pfeiffer, Maurice-Bernard Fleury. Synthesis and in Vitro Evaluation of New 8-Amino-1,4-benzoxazine Derivatives as Neuroprotective Antioxidants. Journal of Medicinal Chemistry, 1999, 42 (24), pp.5043-5052. ⟨10.1021/jm991105j⟩. ⟨hal-02385143⟩
  • Ronan Larget, Brian Lockhart, Bruno Pfeiffer, Anne Neudorffer, Maurice-Bernard Fleury, et al.. Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro. Bioorganic and Medicinal Chemistry Letters, 1999, 9 (20), pp.2929-2934. ⟨10.1016/S0960-894X(99)00504-1⟩. ⟨hal-02385151⟩
  • Nicolas Auzeil, Martine Largeron, Maurice-Bernard Fleury. Acid-catalysed N–alkyl heterolysis of tertiary pyridinecarboxamides and benzamides under mild conditions. Journal of the Chemical Society, Perkin Transactions 2, 1999, 8, pp.1703-1710. ⟨10.1039/a902521i⟩. ⟨hal-02385173⟩
  • Martine Largeron, Maurice-Bernard Fleury. ChemInform Abstract: A Convenient Two-Step One-Pot Electrochemical Synthesis of Novel 8-Amino-1,4-benzoxazine Derivatives Possessing anti-Stress Oxidative Properties.. ChemInform, 1999, 30 (9), pp.no-no. ⟨10.1002/chin.199909186⟩. ⟨hal-02396999⟩
  • Martine Largeron, Anne Neudorffer, Maurice-Bernard Fleury. Further insight into the reaction of electrogenerated o-quinone with amino-alcohols and amines. Products and mechanism. Journal of the Chemical Society, Perkin Transactions 2, 1998, 12, pp.2721-2728. ⟨10.1039/a805507f⟩. ⟨hal-02385193⟩
  • Martine Largeron, Maurice-Bernard Fleury. A convenient two-step one-pot electrochemical synthesis of novel 8-amino-1,4-benzoxazine derivatives possessing anti-stress oxidative properties. Tetrahedron Letters, 1998, 39 (49), pp.8999-9002. ⟨10.1016/S0040-4039(98)02037-1⟩. ⟨hal-02385182⟩
  • Martine Largeron, A. Neudorffer, M.-B. Fleury. ChemInform Abstract: A Simple One-Pot Electrochemical Procedure for the Preparation of Novel 3,4-Aminophenol Derivatives Possessing Anti-Stress Oxidative Properties.. ChemInform, 1998, 29 (39), pp.no-no. ⟨10.1002/chin.199839069⟩. ⟨hal-02396995⟩
  • Martine Largeron, Anne Neudorffer, Maurice-Bernard Fleury. A simple one-pot electrochemical procedure for the preparation of novel 3,4-aminophenol derivatives possessing anti-stress oxidative properties. Tetrahedron Letters, 1998, 39 (28), pp.5035-5038. ⟨10.1016/S0040-4039(98)00995-2⟩. ⟨hal-02385203⟩
  • N. Auzeil, G. Dutruc-Rosset, Martine Largeron. ChemInform Abstract: Electrochemical Removal of the Picolinoyl Group under Mild Acidic Conditions. Application to the Protection of Amines in Peptide Synthesis.. ChemInform, 1997, 28 (30), pp.no-no. ⟨10.1002/chin.199730181⟩. ⟨hal-02396991⟩
  • Martine Largeron, Nicolas Auzeil, Eric Bacqué, Maurice-Bernard Fleury. Influence of steric crowding on the electrochemical reduction of substituted tertiary pyridylcarboxamides in aqueous acidic medium. Journal of the Chemical Society, Perkin Transactions 2, 1997, 3, pp.495-502. ⟨10.1039/a606363b⟩. ⟨hal-02386624⟩
  • Nicolas Auzeil, Gilles Dutruc-Rosset, Martine Largeron. Electrochemical removal of the picolinoyl group under mild acidic conditions. Application to the protection of amines in peptide synthesis. Tetrahedron Letters, 1997, 38 (13), pp.2283-2286. ⟨10.1016/S0040-4039(97)00362-6⟩. ⟨hal-02385211⟩
  • Martine Largeron, D. Langevin-Bermond, N. Auzeil, B. Evers, I. Le Potier, et al.. ChemInform Abstract: Relationship Between Pyridine Nitrogen Basicity and Steric Crowding in an N-Substituted-3-methoxypicolinamide Series.. ChemInform, 1997, 28 (5), pp.no-no. ⟨10.1002/chin.199705239⟩. ⟨hal-02396986⟩
  • Martine Largeron, Nicolas Auzeil, Bouria Dakova, Eric Bacqué, Jean-Marc Paris, et al.. Incidence of the peptidic lactone opening on the electrochemical reduction of pristinamycin IA. Tetrahedron Letters, 1996, 37 (42), pp.7499-7502. ⟨10.1016/0040-4039(96)01729-7⟩. ⟨hal-02386627⟩
  • Martine Largeron, D. Langevin-Bermond, M.-B. Fleury. ChemInform Abstract: Determination of the Sequential Order of Acidity in a Polyhydroxylated Benzophenone Series. Consequence on the Oxidation Reaction in Relation to Hepatotoxicity.. ChemInform, 1996, 27 (32), pp.no-no. ⟨10.1002/chin.199632033⟩. ⟨hal-02397078⟩
  • Martine Largeron, Dominique Langevin-Bermond, Maurice-Bernard Fleury. Determination of the sequential order of acidity in a polyhydroxylated benzophenone series. Consequence on the oxidation reaction in relation to hepatotoxicity. Journal of the Chemical Society, Perkin Transactions 2, 1996, 5, pp.893. ⟨10.1039/p29960000893⟩. ⟨hal-02386633⟩
  • Martine Largeron, H. Dupuy, M.-B. Fleury. ChemInform Abstract: Novel 1,4-Benzoxazine Derivatives of Pharmacological Interest. Electrochemical and Chemical Syntheses.. ChemInform, 1995, 26 (35), pp.no-no. ⟨10.1002/chin.199535201⟩. ⟨hal-02397080⟩
  • Martine Largeron, Hélène Dupuy, Maurice-Bernard Fleury. Novel 1,4-benzoxazine derivatives of pharmacological interest. Electrochemical and chemical syntheses. Tetrahedron, 1995, 51 (17), pp.4953-4968. ⟨10.1016/0040-4020(95)98693-C⟩. ⟨hal-02386640⟩
  • Martine Largeron, M. Vuilhorgne, I. Le Potier, N. Auzeil, E. Bacqué, et al.. ChemInform Abstract: Electrochemical Reduction of Pristinamycin IA and Related Streptogramins in Aqueous Acidic Medium.. ChemInform, 1994, 25 (39), pp.no-no. ⟨10.1002/chin.199439279⟩. ⟨hal-02397082⟩
  • Martine Largeron, M. Vuilhorgne, I.Le Potier, N. Auzeil, E. Bacqué, et al.. Electrochemical reduction of pristinamycin IA and related streptogramins in aqueous acidic medium.. Tetrahedron, 1994, 50 (21), pp.6307-6332. ⟨10.1016/S0040-4020(01)80650-5⟩. ⟨hal-02386645⟩
  • Martine Largeron, M.B. Fleury. Acid‐Base Properties of Pristinamycin IA and Related Compounds. Journal of Pharmaceutical Sciences, 1992, 81 (6), pp.565-568. ⟨10.1002/jps.2600810620⟩. ⟨hal-02386648⟩
  • Martine Largeron, M.-B. Fleury. ChemInform Abstract: Electrochemical Synthesis of 2-Substituted 5-Aminofurans.. ChemInform, 1991, 22 (50), pp.no-no. ⟨10.1002/chin.199150051⟩. ⟨hal-02397086⟩
  • Maurice-Bernard Fleury, Martine Largeron, Thierry Martens. Toward an understanding of the schistosomicidal effect of 4-methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione (oltipraz). Biochemical Pharmacology, 1991, 41 (3), pp.361-367. ⟨10.1016/0006-2952(91)90532-A⟩. ⟨hal-02386654⟩
  • Martine Largeron, Maurice-Bernard Fleury. Electrochemical synthesis of 2-substituted 5-aminofurans.. Tetrahedron Letters, 1991, 32 (5), pp.631-634. ⟨10.1016/S0040-4039(00)74846-5⟩. ⟨hal-02386659⟩
  • M.B. Fleury, Martine Largeron, D. Fleury, J.C. Vernieres. Study of the relationship between nitrogen basicity and receptor affinity in a substituted quinoline series. Journal of Pharmaceutical Sciences, 1990, 79 (9), pp.817-821. ⟨10.1002/jps.2600790915⟩. ⟨hal-02386663⟩
  • Martine Largeron, T. Martens, M. Fleury. ChemInform Abstract: Isolation of Unsymmetrical Disulfides such as (III) and Trisulfides such as (IV) as By-Products in the Course of Electrochemical Reduction of Dithiolethiones, e.g. (I).. ChemInform, 1989, 20 (35), ⟨10.1002/chin.198935224⟩. ⟨hal-02397088⟩
  • Martine Largeron, M.B. Fleury. Acid Catalyzed Hydrolysis of a Series of Zopiclone Analogues. Journal of Pharmaceutical Sciences, 1989, 78 (8), pp.627-631. ⟨10.1002/jps.2600780805⟩. ⟨hal-02386665⟩
  • Martine Largeron, T. Martens, M. Fleury. ChemInform Abstract: Studies of the Reaction of Substituted 1,2-Dithiole-3-thiones and -3-ones with Sodium Cyanide in Acetonitrile.. ChemInform, 1989, 20 (11), ⟨10.1002/chin.198911204⟩. ⟨hal-02397089⟩
  • Martine Largeron, T. Martens, M.B. Fleury. Isolation of unsymmetrical disulphides and trisulphides as by-products in the course of electrochemical reduction of dithiole-thiones. Tetrahedron Letters, 1989, 30 (7), pp.815-816. ⟨10.1016/S0040-4039(01)80622-5⟩. ⟨hal-02386670⟩
  • Martine Largeron, T. Martens, M.B. Fleury. Electrochemical study of the reductive metabolism pathway of 1,2-dithiole-3-thiones. Journal of electroanalytical chemistry and interfacial electrochemistry, 1988, 252 (1), pp.99-108. ⟨10.1016/0022-0728(88)85075-7⟩. ⟨hal-02386675⟩
  • Martine Largeron, T. Martens, M. Fleury. Studies of the reaction of substituted 1,2-dithiole-3-thiones and -3-ones with sodium cyanide in acetonitrile. Journal of Heterocyclic Chemistry, 1988, 25 (4), pp.1223-1225. ⟨10.1002/jhet.5570250434⟩. ⟨hal-02386677⟩
  • Martine Largeron, M.B. Fleury. Electrochemical synthesis and reactivity of 3,5-dicyano-1,2,4,6-tetramethylpyridinium. Journal of electroanalytical chemistry and interfacial electrochemistry, 1988, 246 (2), pp.373-384. ⟨10.1016/0022-0728(88)80173-6⟩. ⟨hal-02386679⟩
  • Martine Largeron, T. Martens, M. Fleury. ChemInform Abstract: Reactivity of Substituted 1,2-Dithiole-3-thiones with Sodium Ethanethiolate: A Convenient Route to a Novel Heterocycle.. ChemInform, 1987, 18 (50), ⟨10.1002/chin.198750362⟩. ⟨hal-02397092⟩
  • Martine Largeron, T. Martens, M.B. Fleury. Reactivity of substituted 1,2-dithiole-3-thiones with sodium ethanethiolate: a convenient route to a novel heterocycle. Tetrahedron, 1987, 43 (15), pp.3421-3428. ⟨10.1016/S0040-4020(01)81633-1⟩. ⟨hal-02386685⟩
  • Martine Largeron, D. Fleury, M.B. Fleury. Study of the reductive metabolism pathway of 4-methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione. An electrochemical approach. Tetrahedron, 1986, 42 (1), pp.409-415. ⟨10.1016/S0040-4020(01)87440-8⟩. ⟨hal-02386687⟩
  • M.B. Fleury, Martine Largeron, M. Barreau, M. Vuilhorgne. Studies of the reaction of 1,2-dithiole-3-thiones with nucleophiles. Tetrahedron, 1985, 41 (18), pp.3705-3715. ⟨10.1016/S0040-4020(01)91391-2⟩. ⟨hal-02386691⟩
  • Martine Largeron, D. Fleury, M.B. Fleury. Electrochemical behaviour of 1,2-dithiole-3-thiones at the mercury electrode in aqueous media. Journal of electroanalytical chemistry and interfacial electrochemistry, 1984, 167 (1-2), pp.183-209. ⟨10.1016/0368-1874(84)87066-5⟩. ⟨hal-02386694⟩

Communications dans un congrès

  • Martine Largeron, Maurice-Bernard Fleury, Margherita Strolin Benedetti. An Electrocatalytic System that Mimics the Catalytic Oxidation of Biogenic Mono- and Polyamines by Semicarbazide-sensitive Amine Oxidases (SSAOs). 216th ECS Meeting (The Electrochemical Society), Oct 2009, Vienna, Austria. pp.97-103, ⟨10.1149/1.3312768⟩. ⟨hal-02384888⟩
  • Martine Largeron, Anne Neudorffer, Mylène Benoît, Maurice-Bernard Fleury. OXIDATION OF PRIMARY ALIPHATIC AMINES CATALYZED BY AN ELECTROGENERATED QUINONOID SPECIES: A SMALL MOLECULE MIMIC OF AMINE OXIDASES. 203rd Electrochemical Society Meeting, The Electrochemical Society (ECS), Apr 2003, Paris, France. pp.185-188. ⟨hal-03118611⟩

Chapitres d'ouvrage

  • Martine Largeron. Recent developments in the one-pot synthesis of 1,4-benzoxazines, 1,4-benzodioxins and their 2,3-dihydro derivatives. Teodoro S. Kaufman; Enrique L. Larghi. Modern Approaches to the Synthesis of O- and N-heterocycles, 3, Research Signpost, 2007, 978-8130801803. ⟨hal-02964693⟩
  • Martine Largeron, Maurice-Bernard Fleury. Electrogenerated quinonoid system: From mimic of amine oxidases cofactor to [4+2] cycloaddition partner. Recent Research Developments in Organic Chemistry, Transworld Research Network, Vol 6 Part II, S. G. Pandalai Managing Editor, 2002. ⟨hal-02964710⟩
  • Martine Largeron, Maurice-Bernard Fleury. Electrogenerated quinones: A powerful tool for the design of novel neuroprotective agents. Recent developments in Medicinal Chemistry, Vol. 1, Transworld Research network, S. G. Pandalai Managing Editor, 2001. ⟨hal-02964719⟩
  • Martine Largeron, Maurice-Bernard Fleury. Electrochemical strategy for the synthesis of molecules endowed with pharmacological properties. Recent Research Developments in Organic Chemistry, Vol.2 Part II, S. G. Pandalai Managing Editor, 1998. ⟨hal-02964731⟩

Brevets

  • Martine Largeron, Pierre Lestage, Brian Lockhart, Maurice-Bernard Fleury. NOVEL 8-AMINO-1,4-BENZOXAZINE COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |. France, Patent n° : WO9962889 (A1). 1999. ⟨hal-03221707⟩
  • Martine Largeron, Maurice-Bernard Fleury, Jean-Marc Maurette. Benzoxazine derivatives, methods for obtaining same, and their use as drugs. United States, Patent n° : US5804580. 1998. ⟨hal-03221705⟩
  • Martine Largeron, Barriere Jean-Claude, Marie-Christine Dubroeucq, Jean-Marc Paris, Maurice-Bernard Fleury. Streptogramin derivatives and their preparation. United States, Patent n° : US5310900. 1994, pp.32. ⟨hal-03221703⟩
  • Martine Largeron, Barriere Jean-Claude, Marie-Christine Dubroeucq, Jean-Marc Paris, Maurice-Bernard Fleury. PROCESS FOR THE PREPARATION OF STREPTOGRAMINE DERIVATIVES.. France, Patent n° : EP0539486 (A1). 1993. ⟨hal-03221701⟩
  • Martine Largeron, Barriere Jean-Claude, Marie-Christine Dubroeucq, Maurice-Bernard Fleury, Jean-Marc Paris. NEW DERIVATIVES OF STREPTOGRAMINES AND PREPARATION THEREOF. United States, Patent n° : WO9201691 (A1). 1992, pp.32. ⟨hal-03221613⟩