M Valéry LARUE

Ingénieur de Recherche CNRSCitCom
Tel :: Numéro

Informations

Docteur de l’Université Pierre et Marie Curie (Ph D)

Recherche

  • Etude structurale de nouvelles cibles anti-infectieuses
  • Spectroscopie RMN des ARNs et des protéines
  • Criblage RMN
  • Modélisation moléculaire
  • Bioinformatique.

Reseachgate

Parties Techniques

  • Responsable du plateau technique RMN
  • CSSI – CNRS
  • Webmaster



31 documents

Articles dans une revue

  • Xiaowei Chen, Pascale Coric, Valéry Larue, Serge Turcaud, Xiao Wang, et al.. The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag. European Journal of Medicinal Chemistry, 2020, 204, pp.112634. ⟨10.1016/j.ejmech.2020.112634⟩. ⟨hal-02914317⟩
  • Clément Dégut, Martine Roovers, Pierre Barraud, Franck Brachet, André Feller, et al.. Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition. Nucleic Acids Research, 2019, 47 (9), pp.4736-4750. ⟨10.1093/nar/gkz230⟩. ⟨hal-02355883⟩
  • Salah Edin El Meshri, Emmanuel Boutant, Assia Mouhand, Audrey Thomas, Valéry Larue, et al.. The NC domain of HIV-1 Gag contributes to the interaction of Gag with TSG101. Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (6), pp.1421-1431. ⟨10.1016/j.bbagen.2018.03.020⟩. ⟨inserm-02154954⟩
  • Valéry Larue, Marjorie Catala, Anissa Belfetmi, Loussiné Zargarian, Olivier Mauffret, et al.. 1H, 13C and 15N backbone and partial side-chain resonance assignments of the C-terminal domain of HIV-1 Pr55Gag encompassed in NCp15. Biomolecular NMR Assignments, 2018, 12 (1), pp.139-143. ⟨10.1007/s12104-017-9796-x⟩. ⟨hal-02370443⟩
  • Clément Dégut, Pierre Barraud, Valéry Larue, Carine Tisné. Backbone resonance assignments of the m1A22 tRNA methyltransferase TrmK from Bacillus subtilis. Biomolecular NMR Assignments, 2016, ⟨10.1007/s12104-016-9680-0⟩. ⟨hal-01307119⟩
  • Dona Sleiman, Serena Bernacchi, Santiago Xavier Guerrero, Franck Brachet, Valéry Larue, et al.. Characterization of RNA binding and chaperoning activities of HIV-1 Vif protein. RNA Biology, 2014, 11 (7), pp.906-920. ⟨10.4161/rna.29546⟩. ⟨hal-02356118⟩
  • Jérémie Piton, Valéry Larue, Yann Thillier, Audrey Dorleans, Olivier Pellegrini, et al.. Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (22), pp.8858-8863. ⟨10.1073/pnas.1221510110⟩. ⟨hal-00829351⟩
  • Thomas Lombès, Roba Moumné, Valéry Larue, Elise Prost, Marjorie Catala, et al.. Investigation of RNA-Ligand Interactions by (19) F NMR Spectroscopy Using Fluorinated Probes.. Angewandte Chemie International Edition, 2012, 51 (38), pp.9530-9534. ⟨10.1002/anie.201204083⟩. ⟨hal-00724894⟩
  • Emilie Goemaere, Armelle Melet, Valéry Larue, Aurélie Lieutaud, Rodolphe Alves de Sousa, et al.. New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity.. Journal of Antimicrobial Chemotherapy, 2012, 67 (6), pp.1392-400. ⟨10.1093/jac/dks058⟩. ⟨hal-00851369⟩
  • Roba Moumné, Marjorie Catala, Valéry Larue, Laurent Micouin, Carine Tisné. Fragment-based design of small RNA binders: promising developments and contribution of NMR.. Biochimie, 2012, 94 (7), pp.1607-1619. ⟨10.1016/j.biochi.2012.02.002⟩. ⟨hal-00692356⟩
  • Roba Moumné, Valéry Larue, Bili Seijo, Thomas Lecourt, Laurent Micouin, et al.. Tether influence on the binding properties of tRNALys3 ligands designed by a fragment-based approach.. Organic & Biomolecular Chemistry, 2010, 8 (5), pp.1154-9. ⟨10.1039/b921232a⟩. ⟨hal-00596199⟩
  • B. Bakan, M. Hamberg, V. Larue, T. Prangé, D. Marion, et al.. The crystal structure of oxylipin-conjugated barley LTP1 highlights the unique plasticity of the hydrophobic cavity of these plant lipid-binding proteins. Biochemical and Biophysical Research Communications, 2009, 390 (3), pp.780-785. ⟨10.1016/j.bbrc.2009.10.049⟩. ⟨hal-02356184⟩
  • Valéry Larue, Bili Seijo, Carine Tisné, Frédéric Dardel. 1H, 13C and 15N NMR assignments of the E. coli peptide deformylase in complex with a natural inhibitor called actinonin. Biomolecular NMR Assignments, 2009, 3 (1), pp.153-155. ⟨10.1007/s12104-009-9164-6⟩. ⟨hal-02370424⟩
  • Sylvain Petit, Yann Duroc, Valéry Larue, Carmela Giglione, Carole Léon, et al.. Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.. ChemMedChem, 2009, 4 (2), pp.261-75. ⟨10.1002/cmdc.200800251⟩. ⟨hal-00853803⟩
  • Marie-Bernard Lascombe, Benedicte Bakan, Nathalie Buhot, Didier Marion, Jean-Pierre Blein, et al.. The structure of “defective in induced resistance” protein of Arabidopsis thaliana , DIR1, reveals a new type of lipid transfer protein. Protein Science, 2008, 17 (9), pp.1522-1530. ⟨10.1110/ps.035972.108⟩. ⟨hal-02864075⟩
  • Adrien Boularot, Carmela Giglione, Sylvain Petit, Yann Duroc, Rodolphe Alves de Sousa, et al.. Discovery and Refinement of a New Structural Class of Potent Peptide Deformylase Inhibitors.. Journal of Medicinal Chemistry, 2007, 50 (1), pp.10-20. ⟨10.1021/jm060910c⟩. ⟨hal-00123257⟩
  • Karine Moncoq, Isabelle Broutin, Valéry Larue, Dominique Perdereau, Katia Cailliau, et al.. The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling. FEBS Letters, 2003, 554 (3), pp.240-246. ⟨10.1016/s0014-5793(03)01095-0⟩. ⟨hal-02370396⟩
  • Laurence Le Moyec, Stéphane Racine, Philippe Le Toumelin, Frederic Adnet, Valéry Larue, et al.. Aminoglycoside and glycopeptide renal toxicity in intensive care patients studied by proton magnetic resonance spectroscopy of urine. Critical Care Medicine, 2002, 30 (6), pp.1242-1245. ⟨10.1097/00003246-200206000-00013⟩. ⟨hal-02370614⟩
  • Ramon Burgada, Théodorine Bailly, Marc Lecouvey, Valéry Larue, Yves Leroux. Synthesis of New Phosphonated Tripod Ligands as Putative New Therapeutic Agents in the Chelation Treatment of Metal Intoxications. European Journal of Organic Chemistry, 2001, 2001 (2), pp.349-352. <a target="_blank" href="https://dx.doi.org/10.1002/1099-0690(200101)2001:23.0.CO;2-F">⟨10.1002/1099-0690(200101)2001:23.0.CO;2-F⟩. ⟨hal-02370643⟩
  • Edith Hantz, Valéry Larue, Patrick Ladam, Laurence Le Moyec, Tam Huynh Dinh. Solution conformation of an RNA–DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand. International Journal of Biological Macromolecules, 2001, 28 (2), pp.273-284. ⟨10.1016/s0141-8130(01)00123-4⟩. ⟨hal-02370571⟩
  • Laurence Le Moyec, Ollivier Legrand, Valéry Larue, Mutsumi Kawakami, Jean Pierre Marie, et al.. Magnetic resonance spectroscopy of cellular lipid extracts from sensitive, resistant and reverting K562 cells and flow cytometry for investigating the P-glycoprotein function in resistance reversion. NMR in Biomedicine, 2000, 13 (2), pp.92-101. <a target="_blank" href="https://dx.doi.org/10.1002/(sici)1099-1492(200004)13:23.0.co;2-r">⟨10.1002/(sici)1099-1492(200004)13:23.0.co;2-r⟩. ⟨hal-02370987⟩
  • L. Le Moyec, M Kawakami, G Leray, V Larue, D Briane, et al.. Magnetic resonance spectroscopy and fluorescence microscopy to investigate mobile lipids in sensitive, resistant and reverting K562 cells and their membranes.. Anticancer Research, 2000, 20 (6B), pp.4513-8. ⟨hal-02370979⟩
  • Laurence Le Moyec, Mutsumi Kawakami, Geneviève Leray, Valéry Larue, Dominique Briane, et al.. Magnetic Resonance Spectroscopy and Fluorescence Microscopy to Investigate Mobile Lipids in Sensitive, Resistant and Reverting K562 Cells and Their Membranes. Anticancer Research, 2000, 20 (6B), pp.4513-8. ⟨hal-02864876⟩
  • Nathalie Evrard-Todeschi, Josyane Gharbi-Benarous, Valéry Larue, Jean-Pierre Girault. Predictive Study by Molecular Modeling To Promote Specific Probes of Glutamate Receptors, Using Methylated Cyclic Glutamic Acid Derivatives ( trans - and cis -ACPD). Comparison with Specific Agonists. Journal of Chemical Information and Computer Sciences, 1998, 38 (4), pp.742-760. ⟨10.1021/ci9802023⟩. ⟨hal-02371099⟩
  • Valéry Larue, Josyane Gharbi-Benarous, Francine Acher, Veerappan Arulmozhi, Carine Tisné, et al.. Solution conformation of α, β or γ-methylglutamyl-containing derivatives as probes of vitamin K-dependent carboxylase using molecular modelling and nuclear magnetic resonance. International Journal of Biological Macromolecules, 1997, 20 (2), pp.131-159. ⟨10.1016/s0141-8130(97)01155-0⟩. ⟨hal-02356235⟩
  • Valéry Larue, Josyane Gharbi-Benarous, Francine C. Acher, Robert Azerad, Jean-Pierre J.-P. Girault. Vitamin K-dependent carboxylase In vitro inhibitory activity of cyclopentane and cyclohexane-derived analogues of glutamic acid and their conformational study by NMR and molecular dynamics in aqueous solution. Journal of Peptide Research, 1997, 49 (1), pp.28-45. ⟨hal-02864862⟩
  • V Larue, J. Gharbi-Benarous, F. Acher, R. Azerad, J Girault. Vitamin K-dependent carboxylase. In vitro inhibitory activity of cyclopentane and cyclohexane-derived analogues of glutamic acid and their conformational study by NMR and molecular dynamics in aqueous solution.. Journal of Peptide Research, 1997, 49 (1), pp.28-45. ⟨hal-02371069⟩
  • Valéry Larue, Josyane Gharbi-Benarous, Francine Archer, Robert Azerad, Jean-Pierre J.-P. Girault. Conformational Study in Water by NMR and Molecular Modeling of Cyclic Glutamic Acid Analogues as Probes of Vitamin K Dependent Carboxylase. Journal of Chemical Information and Computer Sciences, 1996, 36 (4), pp.717-725. ⟨10.1021/ci950153j⟩. ⟨hal-02356232⟩
  • Valéry Larue, Josyane Gharbi-Benarous, Nathalie Evrard-Todeschi, Francine C. Acher, Robert Azerad, et al.. ACPD Ligands for glutamic receptors: Conformational analysis by NMR spectroscopy and molecular dynamics. Simulation in water of glutamic acid analogues containing a cyclopentane ring.. Journal de Chimie Physique, 1995, 92, pp.1809-1812. ⟨hal-02865157⟩
  • Valéry Larue, Josyane Gharbi-Benarous, Francine C. Acher, Giovanni Valle, Marco Crisma, et al.. Conformational analysis by NMR spectroscopy, molecular dynamics simulation in water and X-ray crystallography of glutamic acid analogues: isomers of 1-aminocyclopentane-1,3-dicarboxylic acid. Journal of the Chemical Society, Perkin Transactions 2, 1995, 6, pp.1111. ⟨10.1039/P29950001111⟩. ⟨hal-02371080⟩

Thèses

  • Valéry Larue. Etude conformationnelle par RMN et Modélisation Moléculaire d'analogues de l'acide glutamique comme sonde de la carboxylase vitamine k dépendante. Chemo-informatique. Université Pierre et Marie Curie (Paris 6), 1996. Français. ⟨NNT : ⟩. ⟨tel-02886244⟩